Cyclin H Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00000902-B01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Cyclin H Antibodies »

Product Specifications

Immunogen

CCNH (NP_001230.1, 1 a.a. - 323 a.a.) full-length human protein. MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL

Specificity

CCNH - cyclin H,

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Description

Quality control test: Antibody reactive against mammalian transfected lysate.

Scientific Data Images for Cyclin H Antibody

Western Blot: Cyclin H Antibody [H00000902-B01P]

Western Blot: Cyclin H Antibody [H00000902-B01P]

Western Blot: Cyclin H Antibody [H00000902-B01P] - Analysis of CCNH expression in human kidney.
Immunocytochemistry/ Immunofluorescence: Cyclin H Antibody [H00000902-B01P]

Immunocytochemistry/ Immunofluorescence: Cyclin H Antibody [H00000902-B01P]

Immunocytochemistry/Immunofluorescence: Cyclin H Antibody [H00000902-B01P] - Analysis of purified antibody to CCNH on HeLa cell. (antibody concentration 10 ug/ml)
Western Blot: Cyclin H Antibody [H00000902-B01P]

Western Blot: Cyclin H Antibody [H00000902-B01P]

Western Blot: Cyclin H Antibody [H00000902-B01P] - Analysis of CCNH expression in transfected 293T cell line by CCNH polyclonal antibody. Lane 1: CCNH transfected lysate(35.53 KDa). Lane 2: Non-transfected lysate.

Applications for Cyclin H Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control. It is also useful for IF.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Cyclin H

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. [provided by RefSeq]

Alternate Names

CAK, cyclin H, cyclin-dependent kinase-activating kinase complex subunit, cyclin-H, MO15-associated protein, p34CAK complex subunit, p37CDK-activating kinase complex subunit

Entrez Gene IDs

902 (Human)

Gene Symbol

CCNH

UniProt

NP_001230.1 (Human)

Additional Cyclin H Products

Product Documents for Cyclin H Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Cyclin H Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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