CYP2R1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-32883

Novus Biologicals, part of Bio-Techne
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NBP1-32883
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Rhesus Macaque (97%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CYP2R1 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human CYP2R1. The exact sequence is proprietary.

Localization

Endoplasmic reticulum membrane, Microsome membrane

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

57 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CYP2R1 Antibody

Immunocytochemistry/ Immunofluorescence: CYP2R1 Antibody [NBP1-32883]

Immunocytochemistry/ Immunofluorescence: CYP2R1 Antibody [NBP1-32883]

Immunocytochemistry/Immunofluorescence: CYP2R1 Antibody [NBP1-32883] - Analysis of methanol-fixed HeLa, using antibody at 1:200 dilution.
Immunohistochemistry-Paraffin: CYP2R1 Antibody [NBP1-32883]

Immunohistochemistry-Paraffin: CYP2R1 Antibody [NBP1-32883]

Immunohistochemistry-Paraffin: CYP2R1 Antibody [NBP1-32883] - Mouse liver. Cytochrome P450 2R1 antibody [N1C2] diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
Immunohistochemistry-Paraffin: CYP2R1 Antibody [NBP1-32883]

Immunohistochemistry-Paraffin: CYP2R1 Antibody [NBP1-32883]

Immunohistochemistry-Paraffin: CYP2R1 Antibody [NBP1-32883] - FaDu xenograft, using CYP2R1 antibody at 1:500 dilution. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.
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Applications for CYP2R1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CYP2R1

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency. [provided by RefSeq]

Alternate Names

Cytochrome P450 2R1, cytochrome P450, family 2, R1, cytochrome P450, family 2, subfamily R, polypeptide 1, EC 1.14.13.15, MGC4663, vitamin D 25-hydroxylase

Gene Symbol

CYP2R1

Additional CYP2R1 Products

Product Documents for CYP2R1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CYP2R1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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