Cystatin B/Stefin B Antibody (C7)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-41104

Novus Biologicals, part of Bio-Techne
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NBP3-41104
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Key Product Details

Species Reactivity

Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Lambda Clone # C7

Concentration

1 mg/ml

View all Cystatin B Antibodies »

Product Specifications

Immunogen

Immunized with recombinant Rat Cystatin B/Stefin B (Uniprot#: P01041; Met2-Phe98 (Uniprot#: P01041)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Lambda

Applications for Cystatin B/Stefin B Antibody (C7)

Application
Recommended Usage

ELISA

0.05-2ug/ml

Immunocytochemistry/ Immunofluorescence

5-30ug/ml

Immunohistochemistry-Frozen

5-30ug/ml

Immunohistochemistry-Paraffin

5-30ug/ml

Western Blot

0.5-5ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

0.01M PBS, pH7.4, 50% glycerol

Preservative

0.05% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cystatin B

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1).

Alternate Names

CSTB, Stefin B

Gene Symbol

CSTB

Additional Cystatin B Products

Product Documents for Cystatin B/Stefin B Antibody (C7)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Cystatin B/Stefin B Antibody (C7)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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