Cystatin C Antibody (OTI2C8)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-01875

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI2C8

Concentration

1 mg/ml

View all Cystatin C Antibodies »

Product Specifications

Immunogen

Full length human recombinant protein of human CST3(NP_000090) produced in HEK293T cell.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

13.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Cystatin C Antibody (OTI2C8)

Western Blot: Cystatin C Antibody (OTI2C8) [NBP2-01875]

Western Blot: Cystatin C Antibody (OTI2C8) [NBP2-01875]

Western Blot: Cystatin C Antibody (OTI2C8) [NBP2-01875] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Cystatin C (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-Cystatin C.
Immunohistochemistry-Paraffin: Cystatin C Antibody (OTI2C8) [NBP2-01875]

Immunohistochemistry-Paraffin: Cystatin C Antibody (OTI2C8) [NBP2-01875]

Immunohistochemistry-Paraffin: Cystatin C Antibody (OTI2C8) [NBP2-01875] - Staining of paraffin-embedded Human tonsil using anti-Cystatin C mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Cystatin C Antibody (OTI2C8) [NBP2-01875]

Immunohistochemistry-Paraffin: Cystatin C Antibody (OTI2C8) [NBP2-01875]

Immunohistochemistry-Paraffin: Cystatin C Antibody (OTI2C8) [NBP2-01875] - Staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-Cystatin C mouse monoclonal antibody.
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Applications for Cystatin C Antibody (OTI2C8)

Application
Recommended Usage

Immunohistochemistry

1:150

Immunohistochemistry-Paraffin

1:150

Western Blot

1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Cystatin C

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. [provided by RefSeq].

Alternate Names

ARMD11, CST3, Gamma-trace, Neuroendocrine basic polypeptide, Post-gamma-globulin

Entrez Gene IDs

1471 (Human)

Gene Symbol

CST3

Additional Cystatin C Products

Product Documents for Cystatin C Antibody (OTI2C8)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Cystatin C Antibody (OTI2C8)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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