Cysteinyl Leukotriene R2/CysLTR2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-13897

Novus Biologicals, part of Bio-Techne
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NBP2-13897
NBP2-13897-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Cysteinyl Leukotriene R2/CysLTR2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: KFMSLQPSISVSEMEPNGTFSNNNSRNCTIE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Cysteinyl Leukotriene R2/CysLTR2 Antibody

Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R2/CysLTR2 Antibody [NBP2-13897]

Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R2/CysLTR2 Antibody [NBP2-13897]

Immunohistochemistry-Paraffin: CysLT2 Antibody [NBP2-13897] Staining of human placenta shows cytoplasmic and membranous positivity in trophoblastic cells.

Applications for Cysteinyl Leukotriene R2/CysLTR2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cysteinyl Leukotriene R2/CysLTR2

The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, CysLTR1 and CysLTR2. Both receptors are members of the superfamily of G protein-coupled receptors. CysLTR2 seems to play a major role in endocrine and cardiovascular systems. Stimulation of CysLTR2 by BAY u9773, a partial agonist, induces specific contractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascular endothelium.

Long Name

Cysteinyl Leukotriene Receptor 2

Alternate Names

CysLT2, CysLTR2, Cysteinyl LeukotrieneR2, HG57, HPN321, KPG_011

Gene Symbol

CYSLTR2

Additional Cysteinyl Leukotriene R2/CysLTR2 Products

Product Documents for Cysteinyl Leukotriene R2/CysLTR2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Cysteinyl Leukotriene R2/CysLTR2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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