Cytochrome P450 1A1/1A2 Antibody (MC1) [CoraFluor™ 1]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-08705CL1

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Unconjugated

NBP3-07824

Alexa Fluor 350

NBP3-08705AF350

Alexa Fluor 405

NBP3-08705AF405

Alexa Fluor 488

NBP3-08705AF488

Alexa Fluor 532

NBP3-08705AF532

Alexa Fluor 594

NBP3-08705AF594

Alexa Fluor 647

NBP3-08705AF647

Alexa Fluor 700

NBP3-08705AF700

Alexa Fluor 750

NBP3-08705AF750

Allophycocyanin

NBP3-08705APC

Biotin

NBP3-08705B

DyLight 350

NBP3-08705UV

DyLight 405

NBP3-08705V

DyLight 488

NBP3-08705G

DyLight 550

NBP3-08705R

DyLight 594

NBP3-08705DL594

DyLight 650

NBP3-08705C

DyLight 680

NBP3-08705FR

DyLight 755

NBP3-08705IR

FITC

NBP3-08705F

HRP

NBP3-08705H

Janelia Fluor 525

NBP3-08705JF525

Janelia Fluor 549

NBP3-08705JF549

Janelia Fluor 585

NBP3-08705JF585

Janelia Fluor 635

NBP3-08705JF635

Janelia Fluor 646

NBP3-08705JF646

Janelia Fluor 669

NBP3-08705JF669

PE

NBP3-08705PE

PerCP

NBP3-08705PCP

Forumulation

Catalog #

Azide and BSA Free

NBP3-08705

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Primate

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

CoraFluor 1

Antibody Source

Monoclonal Mouse IgG₁ kappa Clone # MC1

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Cytochrome P450 1A1/1A2 Antibodies »

Product Summary for Cytochrome P450 1A1/1A2 Antibody (MC1) [CoraFluor™ 1]

Immunogen

3-methylcholanthrene induced rat cytochrome P450 protein.

Localization

Cytoplasmic

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁ kappa

Description

CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.

Applications for Cytochrome P450 1A1/1A2 Antibody (MC1) [CoraFluor™ 1]

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: Cytochrome P450 1A1/1A2

P450 enzymes constitute a family of monooxygenase enzymes that are involved in the metabolism of a wide array of endogenous and xenobiotic compounds. Several P450 enzymes have been classified by sequence similarities as members of the CYP1A and CYP2A subfamilies. NADPH cytochrome P450 reductase is a microsomal enzyme responsible for the transfer of electrons from NADPH to cytochrome P450 enzymes during the P450 catalytic cycle. NADPH cytochrome P450 reductase is localized to the endoplasmic reticulum where it is also able to transfer electrons to heme oxygenase and cytochrome beta5. NADPH cytochrome P450 reductase is structurally related to two separate flavoprotein families, ferredoxin nucleotide reductase (FNR) and flavodoxin. Electron transfer of NADPH cytochrome P450 reductase requires the binding of two flavin cofactors, FAD and FMN, to the FNR and flavodoxin domains, respectively.

Alternate Names

AHH, AHRR, aryl hydrocarbon hydroxylase, CP11, CYP1, CYPIA1, cytochrome P1-450, dioxin-inducible, cytochrome P450 1A1, Cytochrome P450 form 6, cytochrome P450, family 1, subfamily A, polypeptide 1, Cytochrome P450-C, Cytochrome P450-P1, EC 1.14.14.1, flavoprotein-linked monooxygenase, P1-450, P450-C, P450DX, subfamily I (aromatic compound-inducible), polypeptide 1, xenobiotic monooxygenase

Gene Symbol

CYP1A1

Additional Cytochrome P450 1A1/1A2 Products

Product Documents for Cytochrome P450 1A1/1A2 Antibody (MC1) [CoraFluor™ 1]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for Cytochrome P450 1A1/1A2 Antibody (MC1) [CoraFluor™ 1]

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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