Cytochrome P450 1A1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00001543-D01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Cytochrome P450 1A1 Antibodies »

Product Specifications

Immunogen

CYP1A1 (NP_000490.1, 1 a.a. - 512 a.a.) full-length human protein. MLFPISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYDHNHQELLSLVNLNNNFGEVVGSGNPADFIPILRYLPNPSLNAFKDLNEKFYSFMQKMVKEHYKTFEKGHIRDITDSLIEHCQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEFSVPLGVKVDMTPIYGLTMKHACCEHFQMQLRS

Specificity

Reacts with cytochrome P450, family 1, subfamily A, polypeptide 1.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Quality control test: Antibody reactive against mammalian transfected lysate.

Scientific Data Images for Cytochrome P450 1A1 Antibody

Western Blot: Cytochrome P450 1A1 Antibody [H00001543-D01P]

Western Blot: Cytochrome P450 1A1 Antibody [H00001543-D01P]

Western Blot: Cytochrome P450 1A1 Antibody [H00001543-D01P] - UroA/UAS03 enhance tight junction proteins in AhR-dependent manner. Cyp1A1 protein levels were measured using immunoblots and quantified band intensities by Image J software. Image collected and cropped by CiteAb from the following publication (//www.nature.com/articles/s41467-018-07859-7) licensed under a CC-BY license.
Western Blot: Cytochrome P450 1A1 Antibody [H00001543-D01P]

Western Blot: Cytochrome P450 1A1 Antibody [H00001543-D01P]

Western Blot: Cytochrome P450 1A1 Antibody [H00001543-D01P] - Analysis of CYP1A1 expression in transfected 293T cell line by CYP1A1 polyclonal antibody.Lane 1: CYP1A1 transfected lysate(58.20 KDa).Lane 2: Non-transfected lysate.

Applications for Cytochrome P450 1A1 Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This antibody is reactive against transfected lysate in WB and as a detection antibody in ELISA.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Cytochrome P450 1A1

This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. [provided by RefSeq]

Long Name

Cytochrome P450 1A1

Alternate Names

CYP1A1, CYPIA1, Cytochrome P450-C, Cytochrome P450-P1

Entrez Gene IDs

1543 (Human)

Gene Symbol

CYP1A1

UniProt

NP_000490.1 (Human)

Additional Cytochrome P450 1A1 Products

Product Documents for Cytochrome P450 1A1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Cytochrome P450 1A1 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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