Cytochrome P450 1A1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB300-608

Novus Biologicals, part of Bio-Techne
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NB300-608
NB300-608-0.025ml
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Cytochrome P450 1A1 Antibodies »

Product Specifications

Immunogen

Purified, His-tagged, full length human P450 1A1 fusion protein.

Specificity

Detects Cytochrome P450 1A1 from human cells. This detects, to a lesser extent, other P450 isoforms.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Cytochrome P450 1A1 Antibody

Western Blot: Cytochrome P450 1A1 Antibody [NB300-608]

Western Blot: Cytochrome P450 1A1 Antibody [NB300-608]

Western Blot: Cytochrome P450 1A1 Antibody [NB300-608] - Analysis of cytochrome P450 1A1 from MCF-7 cell extract.

Applications for Cytochrome P450 1A1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

2 ug/ml

Western Blot

1:500
Application Notes
WB: Detects an approx. 54 kDa protein representing P450 1A1 from MCF-7 cell extract.

Formulation, Preparation, and Storage

Purification

Ammonium sulfate precipitation

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Cytochrome P450 1A1

The Cytochrome P450 (P450) superfamily of enzymes is one of three enzyme systems which metabolize the fatty acid arachadonic acid (AA) to regulators of vascular tone. P450 enzymes are monooxygenase enzymes which require several co-factors such as nicotinamide adenine dinucleotide phosphate (NADPH) and P450 reductase. There are over 200 known genes which encode P450s. Epoxygenases are those P450s which metabolize AA to epoxyeicosatrienoic acid (EETs) and omega-hydroxylases are those P450s which produce 19- and 20-hydroxyeicosatetraenoic acids (19- and 20-HETE). As well as fatty acid metabolism, P450s also metabolize many drugs and toxins. Cytochrome P450 3A4 is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids and rifampicin.

Long Name

Cytochrome P450 1A1

Alternate Names

CYP1A1, CYPIA1, Cytochrome P450-C, Cytochrome P450-P1

Entrez Gene IDs

1543 (Human)

Gene Symbol

CYP1A1

UniProt

P04798 (Human)

Additional Cytochrome P450 1A1 Products

Product Documents for Cytochrome P450 1A1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Cytochrome P450 1A1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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