Cytochrome P450 2C8 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-16078

Novus Biologicals, part of Bio-Techne
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NBP2-16078
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Rhesus Macaque (93%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Cytochrome P450 2C8 Antibodies »

Product Summary for Cytochrome P450 2C8 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human Cytochrome P450 2C8. The exact sequence is proprietary.

Localization

Endoplasmic reticulum membrane; Microsome membrane

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

56 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Cytochrome P450 2C8 Antibody

Western Blot: Cytochrome P450 2C8 Antibody [NBP2-16078]

Western Blot: Cytochrome P450 2C8 Antibody [NBP2-16078]

Western Blot: Cytochrome P450 2C8 Antibody [NBP2-16078] - Various whole cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with CYP2C8 antibody diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.
Immunocytochemistry/ Immunofluorescence: Cytochrome P450 2C8 Antibody [NBP2-16078]

Immunocytochemistry/ Immunofluorescence: Cytochrome P450 2C8 Antibody [NBP2-16078]

Immunocytochemistry/Immunofluorescence: Cytochrome P450 2C8 Antibody [NBP2-16078] - Analysis of methanol-fixed HeLa, using antibody at 1:500 dilution.
Immunohistochemistry-Paraffin: Cytochrome P450 2C8 Antibody [NBP2-16078]

Immunohistochemistry-Paraffin: Cytochrome P450 2C8 Antibody [NBP2-16078]

Immunohistochemistry-Paraffin: Cytochrome P450 2C8 Antibody [NBP2-16078] - Antibody detects CYP2C8 protein at cytosol on hepatoma by immunohistochemical analysis. Sample: Paraffin-embedded hepatoma. CYP2C8 antibody dilution: 1:500.

Applications for Cytochrome P450 2C8 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:1000-1:10000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Cytochrome P450 2C8

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq]

Alternate Names

CPC8, CYPIIC8, cytochrome P450 2C8, Cytochrome P450 form 1, Cytochrome P450 IIC2, Cytochrome P450 MP-12, Cytochrome P450 MP-20, cytochrome P450, family 2, subfamily C, polypeptide 8, cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 8, EC 1.14.14.1, flavoprotein-linked monooxygenase, microsomal monooxygenase, MP-12/MP-20, P450 form 1, S-mephenytoin 4-hydroxylase, xenobiotic monooxygenase

Gene Symbol

CYP2C8

UniProt

P10632 (Human)

Additional Cytochrome P450 2C8 Products

Product Documents for Cytochrome P450 2C8 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Cytochrome P450 2C8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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