Cytohesin 2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-77340

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Canine (100%), Mouse (100%), Porcine (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all Cytohesin 2 Antibodies »

Product Specifications

Immunogen

Peptide with sequence EDGVYEPPDLTP-C corresponding to N-Terminus according to NP_059431.1.

Epitope

EDGVYEPPDLTP

Specificity

This antibody is expected to recognise both reported isoforms (NP_004219.2; NP_059431.1).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Cytohesin 2 Antibody

Western Blot: Cytohesin 2 Antibody [NB100-77340]

Western Blot: Cytohesin 2 Antibody [NB100-77340]

Western Blot: Cytohesin 2 Antibody [NB100-77340] - Staining of Human Brain (Cerebellum) (35 ug protein in RIPA buffer) with antibody at 0.5 ug/mL. Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for Cytohesin 2 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:32000

Western Blot

0.5 - 1.5 ug/mL

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Cytohesin 2

Pleckstrin homology, Sec7 and coiled/coil domains 2 (PSCD2) is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. PSCD2 exhibits GEP activity in vitro with ARF1, ARF3, and ARF6. PSCD2 protein is 83% homologous to PSCD1. Two transcript variants encoding different isoforms have been found for this gene.

Long Name

Cytohesin-2

Alternate Names

ARF exchange factor, ARNO, CYTH2, Protein ARNO, PSCD2, PSCD2L

Entrez Gene IDs

9266 (Human); 19158 (Mouse); 116692 (Rat)

Gene Symbol

CYTH2

UniProt

NP_004219.2 (Human)

Additional Cytohesin 2 Products

Product Documents for Cytohesin 2 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Cytohesin 2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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