Cytohesin 2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-68764

Novus Biologicals, part of Bio-Techne
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NBP2-68764
NBP2-68764-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Cytohesin 2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: REELSEAMSEVEGLEANEGSKTLQRNRKMAMGRKKF

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Cytohesin 2 Antibody

Immunocytochemistry/ Immunofluorescence: Cytohesin 2 Antibody [NBP2-68764]

Immunocytochemistry/ Immunofluorescence: Cytohesin 2 Antibody [NBP2-68764]

Immunocytochemistry/Immunofluorescence: Cytohesin 2 Antibody [NBP2-68764] - Staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.

Applications for Cytohesin 2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
Recommended conditions: Fixation/Permeabilization: PFA/Triton X-100

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cytohesin 2

Pleckstrin homology, Sec7 and coiled/coil domains 2 (PSCD2) is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. PSCD2 exhibits GEP activity in vitro with ARF1, ARF3, and ARF6. PSCD2 protein is 83% homologous to PSCD1. Two transcript variants encoding different isoforms have been found for this gene.

Long Name

Cytohesin-2

Alternate Names

ARF exchange factor, ARNO, CYTH2, Protein ARNO, PSCD2, PSCD2L

Gene Symbol

CYTH2

Additional Cytohesin 2 Products

Product Documents for Cytohesin 2 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Cytohesin 2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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