Cytohesin 3 Antibody (6D3-1A9)

Novus Biologicals, part of Bio-Techne | Catalog # H00009265-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 6D3-1A9

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Cytohesin 3 Antibodies »

Product Specifications

Immunogen

PSCD3 (AAH08191, 1 a.a. ~ 180 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MNRGINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK*

Reactivity Notes

Human. Other species not tested.

Specificity

PSCD3 - pleckstrin homology, Sec7 and coiled-coil domains 3 Please note this antibody was made to Human CYTH3 accession number Q96HS5. This is the 179 amino acid uncharacterized human CYTH3 protein that shares 99% homology with the C-terminal region (221-400) of isoform 1 and 100% homology with the C-terminal region (221-399) of isoform 2 of the characterized human CYTH3 protein (accession number O43739).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Scientific Data Images for Cytohesin 3 Antibody (6D3-1A9)

Western Blot: Cytohesin 3 Antibody (6D3-1A9) [H00009265-M01]

Western Blot: Cytohesin 3 Antibody (6D3-1A9) [H00009265-M01]

Western Blot: Cytohesin 3 Antibody (6D3-1A9) [H00009265-M01] - PSCD3 monoclonal antibody (M01), clone 6D3-1A9 Analysis of PSCD3 expression in Hela S3 NE.
Immunocytochemistry/ Immunofluorescence: Cytohesin 3 Antibody (6D3-1A9) [H00009265-M01]

Immunocytochemistry/ Immunofluorescence: Cytohesin 3 Antibody (6D3-1A9) [H00009265-M01]

Immunocytochemistry/Immunofluorescence: Cytohesin 3 Antibody (6D3-1A9) [H00009265-M01] - Analysis of monoclonal antibody to PSCD3 on HeLa cell. Antibody concentration 10 ug/ml.
Western Blot: Cytohesin 3 Antibody (6D3-1A9) [H00009265-M01]

Western Blot: Cytohesin 3 Antibody (6D3-1A9) [H00009265-M01]

Western Blot: Cytohesin 3 Antibody (6D3-1A9) [H00009265-M01] - Analysis of PSCD3 expression in transfected 293T cell line by PSCD3 monoclonal antibody (M01), clone 6D3-1A9.Lane 1: PSCD3 transfected lysate(46.3 KDa).Lane 2: Non-transfected lysate.
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Applications for Cytohesin 3 Antibody (6D3-1A9)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against cell lysate and recombinant protein for Western Blot. Has also been used for immunofluoresence and ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Cytohesin 3

This gene encodes a member of the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. PSCD family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This encoded protein is involved in the control of Golgi structure and function, and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions, in addition to acting on ARF1.

Alternate Names

ARF nucleotide-binding site opener 3, ARNO3PH, SEC7 and coiled-coil domain-containing protein 3, cytohesin 3, General receptor of phosphoinositides 1, Grp1, GRP1cytohesin-3, pleckstrin homology, Sec7 and coiled-coil domains 3, Protein ARNO3, PSCD3pleckstrin homology, Sec7 and coiled/coil domains 3

Entrez Gene IDs

9265 (Human)

Gene Symbol

CYTH3

OMIM

605081 (Human)

UniProt

AAH08191 (Human)

Additional Cytohesin 3 Products

Product Documents for Cytohesin 3 Antibody (6D3-1A9)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Cytohesin 3 Antibody (6D3-1A9)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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