Cytokeratin 7 Antibody (KRT7/903) - IHC-Prediluted
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-48139
![Immunohistochemistry-Paraffin: Cytokeratin 7 Antibody (KRT7/903) - IHC-Prediluted [NBP2-48139]](https://resources.bio-techne.com/images/products/Cytokeratin-7-Antibody-KRT7-903-IHC-Prediluted-Immunohistochemistry-Paraffin-NBP2-48139-img0003.jpg "Immunohistochemistry-Paraffin: Cytokeratin 7 Antibody (KRT7/903) - IHC-Prediluted [NBP2-48139]")
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Human, Ferret (Negative), Mouse (Negative), Rabbit (Negative), Rat (Negative)
Applications
Immunohistochemistry, Immunohistochemistry-Paraffin
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 kappa Clone # KRT7/903
Format
IHC-Prediluted
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Recombinant full-length human Cytokeratin 7 protein (Uniprot: P08729)
Reactivity Notes
Does not react with Mouse, Rat, Ferret or Rabbit.
Localization
Cytoplasmic
Specificity
Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. Antibody to cytokeratin is useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-).
Marker
Glandular and Transitional Epithelial Marker
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1 kappa
Theoretical MW
54 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Description
The prediluted antibody does not require any mixing, dilution, reconstitution, or titration; the antibody is ready-to-use and optimized for staining.
Scientific Data Images for Cytokeratin 7 Antibody (KRT7/903) - IHC-Prediluted
Immunohistochemistry-Paraffin: Cytokeratin 7 Antibody (KRT7/903) - IHC-Prediluted [NBP2-48139]
Immunohistochemistry-Paraffin: Cytokeratin 7 Antibody (KRT7/903) - IHC-Prediluted [NBP2-48139] - Human Ovarian Carcinoma stained with Cytokeratin 7 Monoclonal Antibody (KRT7/903)Applications for Cytokeratin 7 Antibody (KRT7/903) - IHC-Prediluted
Application
Recommended Usage
Immunohistochemistry
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry-Paraffin
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Hu-chromosome location: 12q13.13 Immunohistochemistry-Paraffin 1 - 2 ug/ml for 30 minutes at RT; Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris Buffer with 1mM EDTA, pH 9.0, for 10 - 20 min followed by cooling at RT for 20 minutes. The 7mL size is a pre-diluted size and no additional dilutions are required before using this item for the intended application.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
10 mM PBS with 0.05% BSA
Format
IHC-Prediluted
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C.
Background: Cytokeratin 7
Alternate Names
CK-7, CK7, K2C7, K7
Gene Symbol
KRT7
Additional Cytokeratin 7 Products
Product Documents for Cytokeratin 7 Antibody (KRT7/903) - IHC-Prediluted
Product Specific Notices for Cytokeratin 7 Antibody (KRT7/903) - IHC-Prediluted
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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