Dact2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76955

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all Dact2 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 12 amino acid synthetic peptide from near the amino terminus of human DACT2. The immunogen is located within amino acids 150 - 200 of Dact2. Amino Acid Squence: GDWRPRSVDETT

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Dact2 Antibody - BSA Free

Western Blot: Dact2 AntibodyBSA Free [NBP1-76955]

Western Blot: Dact2 AntibodyBSA Free [NBP1-76955]

Western Blot: Dact2 Antibody [NBP1-76955] - SK-N-SH cell lysate with Dact2 antibody at 1 ug/ml.
Immunohistochemistry-Paraffin: Dact2 Antibody - BSA Free [NBP1-76955]

Immunohistochemistry-Paraffin: Dact2 Antibody - BSA Free [NBP1-76955]

Immunohistochemistry-Paraffin: Dact2 Antibody [NBP1-76955] - Human brain tissue with Dact2 antibody at 2.5 ug/ml.

Immunocytochemistry/Immunofluorescence: Dact2 Antibody [NBP1-76955] -

Immunocytochemistry/Immunofluorescence: Dact2 Antibody [NBP1-76955] - Immunofluorescence of Dact2 in Human Brain cells with Dact2 antibody at 20 ug/mL.
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Applications for Dact2 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Dact2

The Wnt signaling cascade is a conserved process in multicellular animals that plays important roles during development and can contribute to cancer and other diseases. Many members of this pathway are also expressed in the postnatal tissues such as brain. One such protein is Dact2, a member of the Dact protein family that was initially identified through binding to Disheveled (Dvl), a cytoplasmic protein essential to Wnt signaling. Dact2 is most prominent during the development of the thymus kidneys, and salivary gland. Dact2 is thought to play a role distinct from that of Dact1 with Dact2 having a greater impact on a beta-catenin-independent process termed planar cell polarity/convergent-extension signaling. Furthermore, Dact2 but not Dact1 can inhibit Nodal signaling by promoting the endocytic degradation of TGF-beta receptors. At least two isoforms of Dact2 are known to exist.

Alternate Names

bA503C24.7, C6orf116, chromosome 6 open reading frame 116, dapper homolog 2, dapper homolog 2, antagonist of beta-catenin, dapper homolog 2, antagonist of beta-catenin (xenopus), dapper, antagonist of beta-catenin, homolog 2 (Xenopus laevis), DAPPER2, DPR2, FLJ31232, MGC133141, MGC133142, RP11-503C24.7

Gene Symbol

DACT2

UniProt

NP_999627 (Human)

Additional Dact2 Products

Product Documents for Dact2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Dact2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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