DAP Kinase 2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77291

Novus Biologicals, part of Bio-Techne
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NBP1-77291
NBP1-77291-0.025mg
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all DAPK2 Antibodies »

Product Summary for DAP Kinase 2 Antibody - BSA Free

Immunogen

Antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human DAPK2. This antigenic peptide is identical to the corresponding amino acids of mouse origin (1,2). The immunogen is located within the last 50 amino acids of DAPK2. Amino Acid Squence: ARRKALHPRRRSSTS

Specificity

DAPK2 has no cross responses to DAPK1.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

42 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for DAP Kinase 2 Antibody - BSA Free

Western Blot: DAP Kinase 2 AntibodyBSA Free [NBP1-77291]

Western Blot: DAP Kinase 2 AntibodyBSA Free [NBP1-77291]

Western Blot: DAP Kinase 2 Antibody [NBP1-77291] - Analysis of DAPK2 in A431 (H), mouse spleen (M), and rat kidney (R) lysates with DAPK2 antibody at 1 ug/mL.
Immunohistochemistry: DAP Kinase 2 Antibody - BSA Free [NBP1-77291]

Immunohistochemistry: DAP Kinase 2 Antibody - BSA Free [NBP1-77291]

Immunohistochemistry: DAP Kinase 2 Antibody [NBP1-77291] - DAPK2 in mouse spleen cells with DAPK2 antibody at 2 ug/mL.

Applications for DAP Kinase 2 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunohistochemistry

2 ug/ml

Immunohistochemistry-Paraffin

2 ug/ml

Western Blot

1 ug/ml
Application Notes
An approximately 42 kDa band can be detected in Western Blot.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DAPK2

Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as RIP and DAP kinase, are mediators of apoptosis. DAP kinase (DAPK) is pro-apoptotic calcium-regulated serine/threonine kinase containing death domain. Ectopic expression of DAPK induces cell death and suppresses oncogenic transformation. DAPK mediates IFNgamma induced apoptosis. A novel DAP kinase-related protein was recently identified and designated DAPK2 and DRP-1. Ectopicly expressed DAPK2 induced apoptosis in various types of cells. DAPK has high sequence homology to ZIP kinase and DRAK1/2, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. The messenger RNA of DAPK2 is expressed in multiple human tissues.

Long Name

Death-associated Protein Kinase 2

Alternate Names

DAP Kinase 2, DRP-1

Gene Symbol

DAPK2

UniProt

BAA88063 (Human)

Additional DAPK2 Products

Product Documents for DAP Kinase 2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for DAP Kinase 2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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