DAP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-91031

Novus Biologicals, part of Bio-Techne
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NBP1-91031
NBP1-91031-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all DAP1 Antibodies »

Product Summary for DAP1 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: QFRPNPTLLGNLRQNQVLCPLPYISIFKTRNSSSPNLVYGESGWMSFEDHCAPRGAISRICQDPRKILALVLFQQSP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DAP1 Antibody

Immunocytochemistry/ Immunofluorescence: DAP1 Antibody [NBP1-91031]

Immunocytochemistry/ Immunofluorescence: DAP1 Antibody [NBP1-91031]

Immunocytochemistry/Immunofluorescence: DAP1 Antibody [NBP1-91031] - Immunofluorescent staining of human cell line A-431 shows localization to mitochondria.
Immunohistochemistry-Paraffin: DAP1 Antibody [NBP1-91031]

Immunohistochemistry-Paraffin: DAP1 Antibody [NBP1-91031]

Immunohistochemistry-Paraffin: DAP1 Antibody [NBP1-91031] - Staining of human prostate shows moderate granular positivity in glandular cells.

Applications for DAP1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DAP1

Death associated protein 1 (DAP-1) is a 15-kDa protein that functions as a positive mediator of cell death initiated by interferon (IFN-) gamma (1,2). DAP-1 is proline rich and possesses one SH3 binding motif, as well as several consensus protein kinase phosphorylation sites (1). It is localized to the cytoplasm, but the detailed mechanism of its pro-apoptotic function is unclear. DAP-1 and DAP kinase, a unique, 160-kDa calmodulin-dependent serine/threonine kinase, are both unique candidates for positive mediators of programmed cell death induced by IFN-gamma (3).

Alternate Names

DAP1, DAP-1, death-associated protein, death-associated protein 1, MGC99796

Gene Symbol

DAP

Additional DAP1 Products

Product Documents for DAP1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for DAP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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