DAX1/NR0B1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-52822

Novus Biologicals, part of Bio-Techne
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NBP1-52822
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1 mg/ml

View all DAX1/NR0B1 Antibodies »

Product Summary for DAX1/NR0B1 Antibody

Immunogen

Synthetic peptides corresponding to NR0B1(nuclear receptor subfamily 0, group B, member 1) The peptide sequence was selected from the N terminal of NR0B1. Peptide sequence TSSKQTHVAPAAPEARPGGAWWDRSYFAQRPGGKEALPGGRATALLYRCC. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for DAX1/NR0B1 Antibody

Western Blot: DAX1/NR0B1 Antibody [NBP1-52822]

Western Blot: DAX1/NR0B1 Antibody [NBP1-52822]

Western Blot: DAX1/NR0B1 Antibody [NBP1-52822] - Jurkat cell lysate, Antibody Titration: 2.5ug/ml
Immunohistochemistry-Paraffin: DAX1/NR0B1 Antibody [NBP1-52822]

Immunohistochemistry-Paraffin: DAX1/NR0B1 Antibody [NBP1-52822]

Immunohistochemistry-Paraffin: DAX1/NR0B1 Antibody [NBP1-52822] - Human Intestine Tissue, antibody concentration 4-8ug/ml. Cells with positive label: Epithelial cells of intestinal villus (indicated with arrows) 400X magnification.

Applications for DAX1/NR0B1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DAX1/NR0B1

NR0B1 is a protein that contains a DNA-binding domain. The protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in its gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.

Long Name

Orphan Nuclear Receptor DAX1/Nuclear Receptor Subfamily 0, Group B, Member 1

Alternate Names

AHC, AHCH, NR0B1

Gene Symbol

NR0B1

UniProt

P51843 (Human)

Additional DAX1/NR0B1 Products

Product Documents for DAX1/NR0B1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for DAX1/NR0B1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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