DC-SIGN/CD209 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77284

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all DC-SIGN/CD209 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a synthetic peptide corresponding to 21 amino acids near the center of human DC-DIGN. The immunogen is located within the last 50 amino acids of DC-SIGN. Amino Acid Squence: CSRDEEQFLSPAPATPNPPPA

Marker

Dendritic Cell Marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

47 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for DC-SIGN/CD209 Antibody - BSA Free

Western Blot: DC-SIGN/CD209 AntibodyBSA Free [NBP1-77284]

Western Blot: DC-SIGN/CD209 AntibodyBSA Free [NBP1-77284]

Western Blot: DC-SIGN/CD209 Antibody [NBP1-77284] - Detection of DC-SIGN in human small intestine at (A) 1 and (B) 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: DC-SIGN/CD209 Antibody - BSA Free [NBP1-77284]

Immunocytochemistry/ Immunofluorescence: DC-SIGN/CD209 Antibody - BSA Free [NBP1-77284]

Immunocytochemistry/Immunofluorescence: DC-SIGN/CD209 Antibody [NBP1-77284] - Immunofluorescence of DC-SIGN in Human Lymph Node tissue with DC-SIGN antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: DC-SIGN/CD209 Antibody - BSA Free [NBP1-77284]

Immunohistochemistry-Paraffin: DC-SIGN/CD209 Antibody - BSA Free [NBP1-77284]

Immunohistochemistry-Paraffin: DC-SIGN/CD209 Antibody [NBP1-77284] - Immunohistochemical analysis of DC-SIGN in human lymph node tissue with DC-SIGN antibody at 10 ug/ml.
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Applications for DC-SIGN/CD209 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

10 ug/ml

Immunohistochemistry-Paraffin

10 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DC-SIGN/CD209

Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes, where DCs hand over HIV to CD4+ T lymphocytes. DCs also amplify the amount of virus and extend the duration of viral infectivity. Multiple strains of HIV-1, HIV-2 and SIV bind to DCs via DC-SIGN. ICAM-3 is the natural ligand for DC-SIGN. A DC-SIGN homologue (termed DC-SIGNR, L-SIGN, and DC-SIGN2) was identified recently. DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR. The expression of DC-SIGN was found in mucosal tissues including placenta, small intestine, and rectum.

Long Name

Dendritic Cell-specific ICAM-3-grabbing Non-integrin 1

Alternate Names

CD209, CLEC4L, DC-SIGN1, DCSIGN

Gene Symbol

CD209

UniProt

Q9NNX6

Additional DC-SIGN/CD209 Products

Product Documents for DC-SIGN/CD209 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for DC-SIGN/CD209 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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