Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot (Negative)

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all DC8 Antibodies »

Product Summary for DC8 Antibody

Immunogen

The immunogen recognized by this antibody maps to a region between residue 150 and 200 of human DC8 (C1orf48) using the numbering given in entry NP_056286.2 (GeneID 25936 ).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DC8 Antibody

Immunohistochemistry-Paraffin: DC8 Antibody [NB100-2575]

Immunohistochemistry-Paraffin: DC8 Antibody [NB100-2575]

Immunohistochemistry-Paraffin: DC8 Antibody [NB100-2575] - Detection of human DC8 by immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-DC8 (NB100-2575) used at a dilution of 1:5,000 (0.2ug/ml). Detection: DAB
Immunohistochemistry-Paraffin: DC8 Antibody [NB100-2575]

Immunohistochemistry-Paraffin: DC8 Antibody [NB100-2575]

Immunohistochemistry-Paraffin: DC8 Antibody [NB100-2575] - FFPE section of human breast carcinoma. Affinity purified rabbit anti-DC8 used at a dilution of 1:250.
Immunohistochemistry: DC8 Antibody [NB100-2575]

Immunohistochemistry: DC8 Antibody [NB100-2575]

Immunohistochemistry: DC8 Antibody [NB100-2575] - Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-DC8 used at a dilution of 1:1,000 (1ug/ml). Detection: DAB
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Applications for DC8 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Immunoprecipitation

2-5 ug/mg lysate
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: DC8

This gene encodes a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome-associated structures that attach to microtubules and mediate chromosome movements during cell division. It is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternate Names

C1orf48, chromosome 1 open reading frame 48, DC8, DKFZP566O1646, kinetochore-associated protein NSL1 homolog, MIS14, NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)

Entrez Gene IDs

25936 (Human)

Gene Symbol

NSL1

UniProt

NP_056286.2 (Human)

Additional DC8 Products

Product Documents for DC8 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for DC8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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