DCIR/CLEC4A Antibody (9E8) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-09022

Recombinant Monoclonal Antibody. Clone 9E8 was used by HLDA to establish CD designation.
Novus Biologicals, part of Bio-Techne
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NBP3-09022-0.025mg
NBP3-09022-0.2mg
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow Cytometry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Mouse IgG1 kappa Clone # 9E8

Format

Azide and BSA Free

Concentration

1 mg/ml

View all DCIR/CLEC4A Antibodies »

Product Summary for DCIR/CLEC4A Antibody (9E8) - Azide and BSA Free

Immunogen

This antibody was raised by immunising BALB/c mice with a dendritic cell immunoreceptor ectodomain-human Fc fusion protein.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Applications for DCIR/CLEC4A Antibody (9E8) - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This antibody has been used in flow cytometric analysis of DCIR expression by peripheral blood mononuclear cells (Klechevsky et al, 2010). A recombinant humanised form of this antibody fused to protein antigens is under investigation as an antigen-targeting vaccine (Flamar et al, 2012), and has been shown to trigger antigen-specific CD8+ T cell immunity.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

0.02% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DCIR/CLEC4A

CLEC4A, also known as DCIR, is a member of the C-type lectin/C-type lectin-like (CTL/CTLD) domain superfamily. Members of the CTL/CTLD family have a variety of functions including cell adhesion, glycoprotein turnover and cell-cell signaling. CLEC4A may play a role in regulating immune reactivity. This protein is currently being studied for research on the following diseases and disorders: rheumatoid arthritis, osteoarthritis, pneumonia, influenza, eclampsia and melanoma. CLEC4A is known to have interactions with PTPN6.

Long Name

Dendritic Cell Immunoreceptor

Alternate Names

CD367, CLEC4A, CLECSF6, DDB27, LLIR

Gene Symbol

CLEC4A

Additional DCIR/CLEC4A Products

Product Documents for DCIR/CLEC4A Antibody (9E8) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for DCIR/CLEC4A Antibody (9E8) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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