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Dcp1a Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-2830

Novus Biologicals, part of Bio-Techne
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NB100-2830

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

Product Specifications

Immunogen

Peptide with sequence C-QVLTKNKDNHN corresponding to C-Terminus according to NP_060873.3.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Dcp1a Antibody

Western Blot: Dcp1a Antibody [NB100-2830]

Western Blot: Dcp1a Antibody [NB100-2830]

Western Blot: Dcp1a Antibody [NB100-2830] - Staining of lysate of cell line A431 (35 ug protein in RIPA buffer). Antibody at 1 ug/mL. Detected by chemiluminescence.

Applications for Dcp1a Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:6000

Western Blot

1 - 3 ug/mL
Application Notes
WB: Approx. 75 kDa band observed in human lysates of A431 and HeLa (calculated MW of 63.3 kDa band according to NP_060873.3).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Dcp1a

Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway.

Alternate Names

DCP1 decapping enzyme homolog A (S. cerevisiae), decapping enzyme hDcp1a, EC 3.-, FLJ21691, mRNA-decapping enzyme 1A, Nbla00360, putative protein product of Nbla00360, Smad4-interacting transcriptional co-activator, SMAD4IP1, SMIFHSA275986, Transcription factor SMIF

Entrez Gene IDs

55802 (Human); 75901 (Mouse)

Gene Symbol

DCP1A

Additional Dcp1a Products

Product Documents for Dcp1a Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Dcp1a Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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