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Dcp1a Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-59785

Novus Biologicals, part of Bio-Techne
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NBP2-59785
NBP2-59785-25ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for Dcp1a Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the amino acid sequence: RSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSSASA

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (83%), Rat (82%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Dcp1a Antibody

Immunocytochemistry/ Immunofluorescence: Dcp1a Antibody [NBP2-59785]

Immunocytochemistry/ Immunofluorescence: Dcp1a Antibody [NBP2-59785]

Immunocytochemistry/Immunofluorescence: Dcp1a Antibody [NBP2-59785] - Human cell line U-2 OS shows localization to cytoplasmic bodies. Antibody staining is shown in green.
Dcp1a Antibody Dcp1a Antibody

Dcp1a Antibody [NBP2-59785] -Staining of human cerebral cortex shows moderate to strong cytoplasmic positivity in neurons.

Dcp1a Antibody [NBP2-59785] -Staining of human cerebral cortex shows moderate to strong cytoplasmic positivity in neurons.
Dcp1a Antibody Dcp1a Antibody

Dcp1a Antibody [NBP2-59785] - Staining of human pancreas shows moderate to strong cytoplasmic positivity in exocrine glandular cells.

Dcp1a Antibody [NBP2-59785] - Staining of human pancreas shows moderate to strong cytoplasmic positivity in exocrine glandular cells.

Applications for Dcp1a Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Dcp1a

Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway.

Alternate Names

DCP1 decapping enzyme homolog A (S. cerevisiae), decapping enzyme hDcp1a, EC 3.-, FLJ21691, mRNA-decapping enzyme 1A, Nbla00360, putative protein product of Nbla00360, Smad4-interacting transcriptional co-activator, SMAD4IP1, SMIFHSA275986, Transcription factor SMIF

Gene Symbol

DCP1A

Additional Dcp1a Products

Product Documents for Dcp1a Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Dcp1a Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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