DDX10 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-1577

Novus Biologicals, part of Bio-Techne
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NB100-1577
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Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Human

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

View all DDX10 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 825 and the C-terminus (residue 875) of human DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 10 using the numbering given in entry NP_004389.2 (GeneID 1662).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DDX10 Antibody

Western Blot: DDX10 Antibody [NB100-1577]

Western Blot: DDX10 Antibody [NB100-1577]

Western Blot: DDX10 Antibody [NB100-1577] - Detection of Human DDX10 on HeLa whole cell lystate using NB100-1577. DDX10 was also immunoprecipitated with rabbit anti-DDX10 antibody NB100-1576.

Applications for DDX10 Antibody

Application
Recommended Usage

Immunoprecipitation

1-4 ug/mg of lysate

Western Blot

1:2000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: DDX10

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it may be involved in ribosome assembly. Fusion of this gene and the nucleoporin gene, NUP98, by inversion 11 (p15q22) chromosome translocation is found in the patients with de novo or therapy-related myeloid malignancies.

Alternate Names

DDX10-NUP98 fusion protein type 2, DEAD (Asp-Glu-Ala-Asp) box polypeptide 10, DEAD box protein 10, DEAD box-10, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 10 (RNA helicase), EC 3.6.1, EC 3.6.4.13, HRH-J8, probable ATP-dependent RNA helicase DDX10

Entrez Gene IDs

1662 (Human)

Gene Symbol

DDX10

UniProt

NP_004389.2 (Human)

Additional DDX10 Products

Product Documents for DDX10 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for DDX10 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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