DEAF1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-14928

Novus Biologicals, part of Bio-Techne
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NBP2-14928
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Primate (98%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all DEAF1 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human DEAF1. The exact sequence is proprietary.

Reactivity Notes

Chimpanzee (98%), Mouse (89%), Rat (89%), Chicken (80%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

59 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for DEAF1 Antibody

Western Blot: DEAF1 Antibody [NBP2-14928]

Western Blot: DEAF1 Antibody [NBP2-14928]

Western Blot: DEAF1 Antibody [NBP2-14928] - Sample (30 ug of whole cell lysate) A: A549 7. 5% SDS PAGE; antibody diluted at 1:1000.
Immunohistochemistry-Paraffin: DEAF1 Antibody [NBP2-14928]

Immunohistochemistry-Paraffin: DEAF1 Antibody [NBP2-14928]

Immunohistochemistry-Paraffin: DEAF1 Antibody [NBP2-14928] - Paraffin-embedded Hepatoma, using antibody at 1:500 dilution.

Applications for DEAF1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: DEAF1

Transcription factor that binds to sequence with multiple copies of TTC[CG]G present in its own promoter and that of the HNRPA2B1 gene. Down-regulates transcription of these genes. Binds to the retinoic acid response element (RARE) AGGGTTCACCGAAAGTTCA. Activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase

Alternate Names

deformed epidermal autoregulatory factor 1 (Drosophila), Nuclear DEAF-1-related transcriptional regulator, NUDRdeformed epidermal autoregulatory factor 1 homolog, SPNsuppressin, Zinc finger MYND domain-containing protein 5, ZMYND5Suppressin

Gene Symbol

DEAF1

UniProt

O75398 (Human)

Additional DEAF1 Products

Product Documents for DEAF1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for DEAF1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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