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delta 2 Catenin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-47487

Novus Biologicals, part of Bio-Techne
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NBP2-47487
NBP2-47487-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (93%), Rat (92%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: ASQLERCKLGSETGSMSSMSSAEEQFQWQSQDGQKDIEDELTTGLELVDSCIRSLQESGILDPQDYSTGERPSLLSQSALQLNSKPEGSFQYPASYHSNQTLALGETTPSQLPARGTQARATGQSFSQGTTSRA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for delta 2 Catenin Antibody

Immunohistochemistry-Paraffin: delta 2 Catenin Antibody [NBP2-47487]

Immunohistochemistry-Paraffin: delta 2 Catenin Antibody [NBP2-47487]

Immunohistochemistry-Paraffin: delta 2 Catenin Antibody [NBP2-47487] - Staining in human cerebral cortex and pancreas tissues using anti-CTNND2 antibody. Corresponding CTNND2 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: delta 2 Catenin Antibody [NBP2-47487]

Immunohistochemistry-Paraffin: delta 2 Catenin Antibody [NBP2-47487]

Immunohistochemistry-Paraffin: delta 2 Catenin Antibody [NBP2-47487] - Staining of human pancreas shows low expression as expected.
Immunohistochemistry: delta 2 Catenin Antibody [NBP2-47487]

Immunohistochemistry: delta 2 Catenin Antibody [NBP2-47487]

Immunohistochemistry: delta 2 Catenin Antibody [NBP2-47487] - Staining of human cerebral cortex shows moderate cytoplasmic and nuclear positivity in neuronal cells, neuropil displayed moderate cytoplasmic staining.

Applications for delta 2 Catenin Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: delta 2 Catenin

Delta-Catenin, is a member of the p120 catenin subfamily of catenins. Delta-Catenin/NPRAP was identified as a protein homologous to plakophilin 1 and as a protein interacting with the loop region of presenilin 1 (PS1), the gene most commonly mutated in Alzheimer's disease. Delta-Catenin/NPRAP is almost exclusively expressed in the central nervous system mainly during early brain development. Delta-Catenin/NPRAP has been shown to co-localize and interact with N-cadherin in the mouse brain and to undergo dynamic relocalization during brain development.

Alternate Names

catenin (cadherin-associated protein), delta 2 (neural plakophilin-relatedarm-repeat protein), catenin delta-2, Delta-catenin, GT24T-cell delta-catenin, Neural plakophilin-related ARM-repeat protein, Neurojungin, NPRAPneurojungin

Gene Symbol

CTNND2

Additional delta 2 Catenin Products

Product Documents for delta 2 Catenin Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for delta 2 Catenin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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