Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human, Mouse

Cited:

Mouse

Predicted:

Bovine (100%), Chicken (100%), Primate (100%), Xenopus (100%). Backed by our 100% Guarantee.

Applications

Validated:

Immunoprecipitation (Negative), Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all DENR Antibodies »

Product Specifications

Immunogen

The immunogen for this product maps to a region between residue 148 and 198 of human Density-Regulated Protein using the numbering given in entry NP_003668.2 (GeneID 8562).

Reactivity Notes

Orangutan (100%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DENR Antibody

Western Blot: DENR Antibody [NBP1-50042]

Western Blot: DENR Antibody [NBP1-50042]

Western Blot: DENR Antibody [NBP1-50042] - Detection of human and mouse DRP by western blot (h&m) and immunoprecipitation (h). Samples: Whole cell lysate from HeLa (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded), HEK293T (T; 50 ug) and mouse NIH 3T3 (M; 50 ug) cells. Antibodies: Affinity purified rabbit anti-DRP antibody NBP1-50042 used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 6 ug/mg lysate. DRP was successfully immunoprecipitated by another rabbit anti-DRP antibody, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 30 seconds (A) and 10 seconds (B).

Applications for DENR Antibody

Application
Recommended Usage

Western Blot

1:2000-1:10000
Application Notes
Immunoprecipitation Not recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: DENR

This gene encodes a protein whose expression was found to increase in cultured cells at high density but not during growth arrest. This gene was also shown to have increased expression in cells overexpressing HER-2/neu proto-oncogene. The protein contains an SUI1 domain. In budding yeast, SUI1 is a translation initiation factor that along with eIF-2 and the initiator tRNA-Met, directs the ribosome to the proper translation start site. Proteins similar to SUI have been found in mammals, insects, and plants.

Alternate Names

density-regulated protein, DRP1Protein DRP1, DRPsmooth muscle cell associated protein-3, SMAP-3, Smooth muscle cell-associated protein 3

Entrez Gene IDs

8562 (Human)

Gene Symbol

DENR

UniProt

O43583 (Human)

Additional DENR Products

Product Documents for DENR Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for DENR Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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