Deoxyguanosine kinase Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-84256

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Deoxyguanosine kinase Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: STFVKLLTKTYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLKVQLEPFPEKLLQARKPVQI

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Deoxyguanosine kinase Antibody

Western Blot: Deoxyguanosine kinase Antibody [NBP1-84256]

Western Blot: Deoxyguanosine kinase Antibody [NBP1-84256]

Western Blot: Deoxyguanosine kinase Antibody [NBP1-84256] - Analysis in control (vector only transfected HEK293T lysate) and DGUOK over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunohistochemistry-Paraffin: Deoxyguanosine kinase Antibody [NBP1-84256]

Immunohistochemistry-Paraffin: Deoxyguanosine kinase Antibody [NBP1-84256]

Immunohistochemistry-Paraffin: Deoxyguanosine kinase Antibody [NBP1-84256] - Staining of human smooth muscle shows strong cytoplasmic positivity in smooth muscle cells.
Immunohistochemistry-Paraffin: Deoxyguanosine kinase Antibody [NBP1-84256]

Immunohistochemistry-Paraffin: Deoxyguanosine kinase Antibody [NBP1-84256]

Immunohistochemistry-Paraffin: Deoxyguanosine kinase Antibody [NBP1-84256] - Staining of human Lymph node shows moderate cytoplasmic positivity in non-germinal center cells.
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Applications for Deoxyguanosine kinase Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20-1:50

Western Blot

1:100-1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Deoxyguanosine kinase

In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.

Alternate Names

deoxyguanosine kinase, deoxyguanosine kinase, mitochondrial, DGK, dGKmitochondrial deoxyguanosine kinase, EC 2.7.1.113, MTDPS3

Gene Symbol

DGUOK

Additional Deoxyguanosine kinase Products

Product Documents for Deoxyguanosine kinase Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Deoxyguanosine kinase Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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