Desmocollin-2 Antibody (003)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-90904

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP2-90904-100ul
NBP2-90904-50ul
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Key Product Details

Species Reactivity

Validated:

Rat

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 003

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Desmocollin-2 Antibodies »

Product Summary for Desmocollin-2 Antibody (003)

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Rat Desmocollin-2 (Uniprot#: Q3T1K6; Met1-Pro694).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for Desmocollin-2 Antibody (003)

Immunohistochemistry-Paraffin: Desmocollin-2 Antibody (003) [NBP2-90904]

Immunohistochemistry-Paraffin: Desmocollin-2 Antibody (003) [NBP2-90904]

Immunohistochemistry-Paraffin: Desmocollin-2 Antibody (003) [NBP2-90904] - Staining of rat DSC2 in rat heart with rabbit monoclonal antibody 1:500.

Applications for Desmocollin-2 Antibody (003)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:250-1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Desmocollin-2

Desmocollin 2 is encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11. Alternative splicing results in two transcript variants encoding distinct isoforms.

Alternate Names

ARVD11, CDHF2, Desmocollin2, DG2, DSC2

Gene Symbol

DSC2

Additional Desmocollin-2 Products

Product Documents for Desmocollin-2 Antibody (003)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Desmocollin-2 Antibody (003)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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