Desmoglein-3 Antibody (5H10) [Janelia Fluor® 646]
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-11310JF646
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Validated:
Human
Applications
Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Western Blot
Label
Janelia Fluor 646
Antibody Source
Monoclonal Mouse IgG1 kappa Clone # 5H10
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Summary for Desmoglein-3 Antibody (5H10) [Janelia Fluor® 646]
Immunogen
Recombinant human Desmoglein-3 extracellular protein fragment (Uniprot: P32926)
Localization
Cell Surface
Specificity
Recognizes a protein of 130kDa, identified as Desmoglein-3 (DSG3). This monoclonal antibody is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members are identified and all are members of the cadherin cell adhesion molecule superfamily.
Marker
Squamous Cell Marker
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1 kappa
Applications for Desmoglein-3 Antibody (5H10) [Janelia Fluor® 646]
Application
Recommended Usage
Flow Cytometry
Optimal dilutions of this antibody should be experimentally determined.
Immunocytochemistry/ Immunofluorescence
Optimal dilutions of this antibody should be experimentally determined.
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Desmoglein-3
Alternate Names
CDHF6, Desmoglein3, DSG3
Gene Symbol
DSG3
Additional Desmoglein-3 Products
Product Documents for Desmoglein-3 Antibody (5H10) [Janelia Fluor® 646]
Product Specific Notices for Desmoglein-3 Antibody (5H10) [Janelia Fluor® 646]
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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