Desmoglein-3 Antibody (rDSG3/8611) [Janelia Fluor® 585]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-24060JF585

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-24060JF585
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

Janelia Fluor 585

Antibody Source

Recombinant Monoclonal Mouse IgG1 kappa Clone # rDSG3/8611

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

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Product Summary for Desmoglein-3 Antibody (rDSG3/8611) [Janelia Fluor® 585]

Immunogen

Recombinant fragment (around aa300-500) of human Desmoglein-3 protein (exact sequence is proprietary)

Localization

Cell surface

Specificity

This monoclonal antibody is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family.

Marker

Squamous Cell Marker

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Applications for Desmoglein-3 Antibody (rDSG3/8611) [Janelia Fluor® 585]

Application
Recommended Usage

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Desmoglein-3

Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

Alternate Names

CDHF6, Desmoglein3, DSG3

Gene Symbol

DSG3

Additional Desmoglein-3 Products

Product Documents for Desmoglein-3 Antibody (rDSG3/8611) [Janelia Fluor® 585]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Desmoglein-3 Antibody (rDSG3/8611) [Janelia Fluor® 585]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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