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DFNB31 Antibody (1D9)

Novus Biologicals, part of Bio-Techne | Catalog # H00025861-M02

Novus Biologicals, part of Bio-Techne
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H00025861-M02

Key Product Details

Species Reactivity

Human

Applications

ELISA, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 1D9

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

DFNB31 (NP_056219, 808 a.a. ~ 907 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. GLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGLTLRGKEHREAARIIAEAFKTKDRDYIDFLVTEFNVML

Reactivity Notes

Human. Other species not tested.

Specificity

DFNB31 - deafness, autosomal recessive 31

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Scientific Data Images for DFNB31 Antibody (1D9)

Sandwich ELISA: DFNB31 Antibody (1D9) [H00025861-M02] - Detection limit for recombinant GST tagged DFNB31 is approximately 0.03ng/ml as a capture antibody.

Applications for DFNB31 Antibody (1D9)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: DFNB31

In rat brain, Cip98 interacts with a calmodulin-dependent serine kinase, CASK (MIM 300172), and may be involved in the formation of scaffolding protein complexes that facilitate synaptic transmission in the central nervous system (CNS) (Yap et al., 2003 [PubMed 12641734]). Mutations in this gene, also known as WHRN, cause DFNB31 (MIM 607084).[supplied by OMIM]

Alternate Names

Autosomal recessive deafness type 31 protein, CIP98DKFZp434N014, deafness, autosomal recessive 31, DFNB 31, KIAA1526whirlin, USH2DWI, whrn, WHRNCASK-interacting protein CIP98

Entrez Gene IDs

25861 (Human)

Gene Symbol

WHRN

OMIM

607084 (Human)

Additional DFNB31 Products

Product Documents for DFNB31 Antibody (1D9)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for DFNB31 Antibody (1D9)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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