DFNB31 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-10840

Novus Biologicals, part of Bio-Techne
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NBP3-10840-100ul
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Key Product Details

Species Reactivity

Validated:

Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

View all DFNB31 Antibodies »

Product Summary for DFNB31 Antibody

Immunogen

The immunogen is a synthetic peptide directed towards the middle terminal region of mouse DFNB31 (NP_001008791.1). Peptide sequence VLRREIESMKARQPPGPGVGDTYSMVSYSDTGSSTGSHGTSTTVSSARER

Clonality

Polyclonal

Host

Rabbit

Theoretical MW

42 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for DFNB31 Antibody

Western Blot: DFNB31 Antibody [NBP3-10840]

Western Blot: DFNB31 Antibody [NBP3-10840]

Western Blot: DFNB31 Antibody [NBP3-10840] - Western blot analysis of DFNB31 in Mouse Kidney lysates. Antibody dilution at 1ug/ml

Applications for DFNB31 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DFNB31

DFNB31 (deafness autosomal recessive 31) is a PDZ scaffold protein which is necessary for elongation and maintenance of stereocilia in the inner and outer hair cells in the organ of Corti in the inner ear. It is also expressed in retinal photoreceptor cells. Mutations in this gene, also known as Whirlin, are associated with non syndromic sensorineural deafness autosomal recessive type 31 and retinitis pigmentosa. DFNB31 interacts with a calmodulin dependent serine kinase, CASK, and may be involved in the formation of scaffolding protein complexes that facilitate synaptic transmission in the central nervous system.

Alternate Names

Autosomal recessive deafness type 31 protein, CIP98DKFZp434N014, deafness, autosomal recessive 31, DFNB 31, KIAA1526whirlin, USH2DWI, whrn, WHRNCASK-interacting protein CIP98

Gene Symbol

WHRN

Additional DFNB31 Products

Product Documents for DFNB31 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for DFNB31 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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