DGK-zeta Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-13918

Novus Biologicals, part of Bio-Techne
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NBP2-13918
NBP2-13918-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (92%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all DGK-zeta Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the amino acids: EHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLPTSPCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DGK-zeta Antibody

Immunocytochemistry/ Immunofluorescence: DGK-zeta Antibody [NBP2-13918]

Immunocytochemistry/ Immunofluorescence: DGK-zeta Antibody [NBP2-13918]

Immunocytochemistry/Immunofluorescence: DGK-zeta Antibody [NBP2-13918] - Staining of human cell line A-431 shows localization to nuclear speckles. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: DGK-zeta Antibody [NBP2-13918]

Immunohistochemistry-Paraffin: DGK-zeta Antibody [NBP2-13918]

Immunohistochemistry-Paraffin: DGK-zeta Antibody [NBP2-13918] - Staining of human liver shows no positivity in hepatocytes.
Immunohistochemistry-Paraffin: DGK-zeta Antibody [NBP2-13918]

Immunohistochemistry-Paraffin: DGK-zeta Antibody [NBP2-13918]

Immunohistochemistry-Paraffin: DGK-zeta Antibody [NBP2-13918] - Staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.
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Applications for DGK-zeta Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. For ICC/IF Fixation/Permeabilization: PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DGK-zeta

DGKZ, also known as Diacylglycerol kinase zeta, consists of six isoforms of sizes 124.1 kDa, 104 kDa, 106 kDa, 104.1 kDa, 104.6 kDa, and 101.2 kDa and is involved in regulating the amount of diacylglycerol in signal transduction pathways as a member of the eukaryotic diacylglycerol kinase family. Current research is exploring the effect of the protein on diseases such as malaria, retinoblastoma, cerebritis, bipolar disorder, and cerebral infarction. The protein interacts with RB1, RBL1, RBL2, MAPK6, and GCOM1 while in glycerolipid metabolism, hemostasis, PIP2 hydrolysis, and signal transduction pathways.

Long Name

Diacylglycerol Kinase

Alternate Names

DGKZ, DGKzeta

Gene Symbol

DGKZ

Additional DGK-zeta Products

Product Documents for DGK-zeta Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for DGK-zeta Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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