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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

DIS3 antibody was raised against an 18 amino acid peptide near the amino terminus of human DIS3. The immunogen is located within amino acids 90 - 140 of DIS3. Amino Acid Squence: YKRIRDVTNNQEKHFYTF

Specificity

Multiple isoforms of DIS3 are known to exist.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

103 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for DIS3 Antibody - BSA Free

Western Blot: DIS3 AntibodyBSA Free [NBP2-81804]

Western Blot: DIS3 AntibodyBSA Free [NBP2-81804]

Western Blot: DIS3 Antibody [NBP2-81804] - Analysis of DIS3 in human ovary tissue lysate with DIS3 antibody at 1 ug/ml.
DIS3 Antibody - BSA Free

Immunohistochemistry: DIS3 Antibody - BSA Free [NBP2-81804] -

Immunohistochemistry: DIS3 Antibody - BSA Free [NBP2-81804] - Immunohistochemistry of DIS3 in mouse testis tissue with DIS3 antibody at 2.5 u/ml.
DIS3 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: DIS3 Antibody - BSA Free [NBP2-81804] -

Immunocytochemistry/ Immunofluorescence: DIS3 Antibody - BSA Free [NBP2-81804] - Immunofluorescence of DIS3 in mouse testis tissue with DIS3 antibody at 20 ug/ml.

Applications for DIS3 Antibody - BSA Free

Application
Recommended Usage

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DIS3

DIS3 is a component of the exosome 3'->5' exoribonuclease complex. Required for the 3'-processing of the 7S pre-RNA to the mature nuclear complex. Also associated with the GTPase Ran. Has a 3'-5' exonuclease activity

Alternate Names

2810028N01Rik, DIS3 mitotic control homolog (S. cerevisiae), dis3p, DKFZp667L1817, EC 3.1.13, EC 3.1.13.-, EC 3.1.26.-, EXOSC11, exosome complex exonuclease RRP44, exosome component 11, FLJ10484, KIAA1008RP11-342J4.3, MGC33035, mitotic control protein dis3 homolog, Protein DIS3 homolog, Ribosomal RNA-processing protein 44, RRP44bA555G22.1

Gene Symbol

DIS3

Additional DIS3 Products

Product Documents for DIS3 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for DIS3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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