Dishevelled-2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-58849

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Rat

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all Dishevelled-2 Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to DVL2(dishevelled, dsh homolog 2 (Drosophila)) The peptide sequence was selected from the N terminal of DVL2. Peptide sequence AGSSTGGGGVGETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQRPA. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for Dishevelled-2 Antibody

Western Blot: Dishevelled-2 Antibody [NBP1-58849]

Western Blot: Dishevelled-2 Antibody [NBP1-58849]

Western Blot: Dishevelled 2 Antibody [NBP1-58849] - Titration: 0.2-1 ug/ml, Positive Control: Transfected 293T.
Immunohistochemistry-Paraffin: Dishevelled-2 Antibody [NBP1-58849]

Immunohistochemistry-Paraffin: Dishevelled-2 Antibody [NBP1-58849]

Immunohistochemistry-Paraffin: Dishevelled 2 Antibody [NBP1-58849] - Human Small intestine, muscularis propria, 5 ug/ml.

Applications for Dishevelled-2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Dishevelled-2

DVL2 is a member of the dishevelled (dsh) protein family. It is a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Alternate Names

Dishevelled2, DVL2

Gene Symbol

DVL2

UniProt

O14641

Additional Dishevelled-2 Products

Product Documents for Dishevelled-2 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Dishevelled-2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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