DLG1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-20907

Novus Biologicals, part of Bio-Techne
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NBP1-20907
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all DLG1 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-NSKTRDKGEIPDD corresponding to internal region according to NP_001091894.1, NP_004078.2.

Epitope

C terminus

Specificity

This antibody is expected to recognize both reported isoforms (NP_001091894.1and NP_004078.2).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for DLG1 Antibody

Western Blot: DLG1 Antibody [NBP1-20907]

Western Blot: DLG1 Antibody [NBP1-20907]

Western Blot: DLG1 Antibody [NBP1-20907] - (0.3ug/ml) staining of KELLY lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for DLG1 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:16000

Western Blot

0.3 - 1 ug/ml
Application Notes
WB: Approx. 150 kDa band observed in KELLY lysate (calculated MW of 103 kDa band according to NP_004078.2). The observed molecular weight corresponds to earlier findings with different antibodies from other sources.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: DLG1

DLG1(disks large homolog 1), also known as SAP97(synapse-associated protein 97), is a scaffolding protein that contains three PDZ domains, one SH3 domain, one L27 domain, and one guanylate kinase-like domain. DLG1has been found to control ion channel clustering at post-synaptic densities in neural cells and to also play a role in adherens junction assembly, and the recruitment of signaling molecules to discreet plasma membrane domains.

Alternate Names

discs, large homolog 1 (Drosophila), disks large homolog 1, DKFZp761P0818, DKFZp781B0426, hDlg, large (Drosophila) homolog 1, presynaptic protein SAP97

Entrez Gene IDs

1739 (Human); 13383 (Mouse); 25252 (Rat)

Gene Symbol

DLG1

UniProt

NP_001091894.1 (Human)

Additional DLG1 Products

Product Documents for DLG1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for DLG1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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