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DLL3 Antibody (rovalpituzumab) - Humanized

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-28317

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-28317-50ug
NBP3-28317-100ug

Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Functional

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Human IgG1 Clone # rovalpituzumab

Concentration

LYOPH mg/ml

Product Specifications

Immunogen

DLL3

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Endotoxin Level

< 0.001EU/ug,determined by LAL method.

Description

Expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

Also known as 'rovalpituzumab'.

Upon receipt, store immediately at -20C or lower for 24 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.

Scientific Data Images for DLL3 Antibody (rovalpituzumab) - Humanized

DLL3 Antibody (rovalpituzumab) - Humanized

ELISA: DLL3 Antibody (rovalpituzumab) - Humanized[NBP3-28317] -

Immobilized human DLL3 His at 2 ug/mL can bind DLL3 Antibody (rovalpituzumab) - Humanized, EC50=0.01407 ug/mL.
DLL3 Antibody (rovalpituzumab) - Humanized

Flow Cytometry: DLL3 Antibody (rovalpituzumab) - Humanized[NBP3-28317] -

Human DLL3 HEK293 cells were stained with DLL3 Antibody (rovalpituzumab) - Humanized and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=0.01586 ug/mL.

Applications for DLL3 Antibody (rovalpituzumab) - Humanized

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Formulation

Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: DLL3

The DLL3 gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostos

Long Name

Delta-like 3

Alternate Names

Pudgy, SCDO1

Gene Symbol

DLL3

UniProt

Additional DLL3 Products

Product Documents for DLL3 Antibody (rovalpituzumab) - Humanized

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for DLL3 Antibody (rovalpituzumab) - Humanized

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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