DMP-1 Antibody [PE]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-99906PE

Novus Biologicals, part of Bio-Techne
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NBP2-99906PE
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Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA

Label

PE (Excitation = 488 nm, Emission = 575 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

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Product Summary for DMP-1 Antibody [PE]

Immunogen

Produced in rabbits immunized with purified, recombinant Human DMP-1 (Uniprot#: Q13316-1; Met 1-Tyr 513)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for DMP-1 Antibody [PE]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: DMP-1

Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. The gene structure is conserved in mammals. Two transcript variants encoding different isoforms have been described for this gene.

Long Name

Dentin Matrix Protein 1

Alternate Names

DMP1

Gene Symbol

DMP1

Additional DMP-1 Products

Product Documents for DMP-1 Antibody [PE]

Product Datasheets

Certificate of Analysis

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Product Specific Notices for DMP-1 Antibody [PE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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