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DMRT1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-16179

Novus Biologicals, part of Bio-Techne
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NBP2-16179

Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for DMRT1 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human DMRT1. The exact sequence is proprietary.

Reactivity Notes

Pig (84%).

Localization

Nucleus

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

39 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for DMRT1 Antibody

Western Blot: DMRT1 Antibody [NBP2-16179]

Western Blot: DMRT1 Antibody [NBP2-16179]

Western Blot: DMRT1 Antibody [NBP2-16179] - Sample (30 ug of whole cell lysate) A: K562 10% SDS PAGE gel, diluted at 1:3000.

Applications for DMRT1 Antibody

Application
Recommended Usage

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: DMRT1

This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. [provided by RefSeq]

Alternate Names

DM domain expressed in testis 1, DMT1DM domain expressed in testis protein 1, doublesex and mab-3 related transcription factor 1, doublesex- and mab-3-related transcription factor 1

Gene Symbol

DMRT1

Additional DMRT1 Products

Product Documents for DMRT1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for DMRT1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.