DMRT2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86361

Novus Biologicals, part of Bio-Techne
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NBP1-86361
NBP1-86361-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all DMRT2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: VPGPDYNSYKSAYSPSPVEPPSKDFCNFLPTCLDLTMQYSGSGNMELISSNVSVATTYRQYPLSSRFLVWPKCGPISDTLLYQQCLLNATTSVQALKPGASWDLKGARVQDGLSAEQDMMPSKLEGSLVLPHTPEIQTTRSDLQGHQAVP

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (86%), Rat (85%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DMRT2 Antibody

Immunohistochemistry-Paraffin: DMRT2 Antibody [NBP1-86361]

Immunohistochemistry-Paraffin: DMRT2 Antibody [NBP1-86361]

Immunohistochemistry-Paraffin: DMRT2 Antibody [NBP1-86361] - Staining of human colon shows distinct cytoplasmic positivity in glandular cells.

Applications for DMRT2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DMRT2

DMRT2, also known as Doublesex and mab-3-related transcription factor 2, consists of a 61.8 kDa, a 24.5 kDa, and a 36.9 kDa isoform and is involved in regulating activation of the gene MYF5 as a transcription factor during embryogenesis and somite development. Current research has linked the protein to diseases such as sex reversal, attention deficit hyperactivity disorder, leukemia, anemia, and gonadal dysgenesis. The protein interacts with UBC, CCDC18, BCLAF1, RPS3, and MYBBP1A in transcription pathways.

Alternate Names

doublesex and mab-3 related transcription factor 2, doublesex- and mab-3-related transcription factor 2, Doublesex-like 2 protein, DSXL2, DSXL-2, terra-like protein

Gene Symbol

DMRT2

Additional DMRT2 Products

Product Documents for DMRT2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for DMRT2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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