DNAL1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76932

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (100%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all DNAL1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human DNAL1. The immunogen is located within the last 50 amino acids of DNAL1. Amino Acid Squence: KKLDGTPVIKEDEEEDN

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DNAL1 Antibody - BSA Free

Western Blot: DNAL1 AntibodyBSA Free [NBP1-76932]

Western Blot: DNAL1 AntibodyBSA Free [NBP1-76932]

Western Blot: DNAL1 Antibody [NBP1-76932] - 3T3 cell lysate with DNAL1 antibody at (A) 1 and (B) 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: DNAL1 Antibody - BSA Free [NBP1-76932]

Immunocytochemistry/ Immunofluorescence: DNAL1 Antibody - BSA Free [NBP1-76932]

Immunocytochemistry/Immunofluorescence: DNAL1 Antibody [NBP1-76932] - Immunofluorescence of DNAL1 in 3T3 cells with DNAL1 antibody at 20 ug/mL. Green: (NBP1-76932); Blue: DAPI staining
Immunocytochemistry/ Immunofluorescence: DNAL1 Antibody - BSA Free [NBP1-76932]

Immunocytochemistry/ Immunofluorescence: DNAL1 Antibody - BSA Free [NBP1-76932]

Immunocytochemistry/Immunofluorescence: DNAL1 Antibody [NBP1-76932] - 3T3 cells with DNAL1 antibody at 2.5 ug/ml.
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Applications for DNAL1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

2.5 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DNAL1

DNAL1 was identified as a potential candidate gene for primary ciliary dyskinesia (PCD), a genetically heterologous disorder characterized by chronic infections of the upper and lower airways that often leads to permanent lung damage, randomization of left/right body symmetry, and reduced fertility. DNAL1 is reported to be expressed solely in tissues carrying motile cilia for flagella and interacts with DNAH5, a protein that when mutated has been shown to result in PCD. It has been suggested that DNAL1 serves a regulatory function for DNAH5 activity in outer dynein arms of sperm flagella, respiratory cilia, and ependymal cilia. DNAL1 has also been recently identified as an HIV dependency factor (HDF), suggesting that DNAL1 may be an important drug target in HIV treatment. At least two isoforms of DNAL1 are known to exist.

Alternate Names

C14orf168MGC12435,1700010H15RiK, chromosome 14 open reading frame 168, dynein light chain 1, axonemal, dynein, axonemal, light chain 1

Gene Symbol

DNAL1

UniProt

NP_113615 (Human)

Additional DNAL1 Products

Product Documents for DNAL1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for DNAL1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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