DNase II Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00001777-D01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all DNase II Antibodies »

Product Specifications

Immunogen

DNASE2 (NP_001366.1, 1 a.a. - 360 a.a.) full-length human protein. MIPLLLAALLCVPAGALTCYGDSGQPVDWFVVYKLPALRGSGEAAQRGLQYKYLDESSGGWRDGRALINSPEGAVGRSLQPLYRSNTSQLAFLLYNDQPPQPSKAQDSSMRGHTKGVLLLDHDGGFWLVHSVPNFPPPASSAAYSWPHSACTYGQTLLCVSFPFAQFSKMGKQLTYTYPWVYNYQLEGIFAQEFPDLENVVKGHHVSQEPWNSSITLTSQAGAVFQSFAKFSKFGDDLYSGWLAAALGTNLQVQFWHKTVGILPSNCSDIWQVLNVNQIAFPGPAGPSFNSTEDHSKWCVSPKGPWTCVGDMNRNQGEEQRGGGTLCAQLPALWKAFQPLVKNYQPCNGMARKPSRAYKI

Specificity

Reacts with deoxyribonuclease II, lysosomal.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Quality control test: Antibody reactive against mammalian transfected lysate.

Scientific Data Images for DNase II Antibody

Western Blot: DNase II Antibody [H00001777-D01P]

Western Blot: DNase II Antibody [H00001777-D01P]

Western Blot: DNase II Antibody [H00001777-D01P] - Analysis of DNASE2 expression in transfected 293T cell line by DNASE2 polyclonal antibody.Lane 1: DNASE2 transfected lysate(39.60 KDa).Lane 2: Non-transfected lysate.

Applications for DNase II Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This antibody is reactive against transfected lysate in WB and as a detection antibody in ELISA.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: DNase II

This gene encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record. [provided by RefSeq]

Alternate Names

Acid DNase, Deoxyribonuclease II alpha, deoxyribonuclease II, lysosomal, deoxyribonuclease-2-alpha, DNase II alpha, DNase II, lysosomal, DNASE2A, DNL, DNL2, EC 3.1.22.1, Lysosomal DNase II, R31240_2

Entrez Gene IDs

1777 (Human)

Gene Symbol

DNASE2

UniProt

NP_001366.1 (Human)

Additional DNase II Products

Product Documents for DNase II Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for DNase II Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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