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DNASE1 Antibody (2-1#)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-41461

Novus Biologicals, part of Bio-Techne
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NBP3-41461

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 2-1#

Concentration

1 mg/ml

Product Specifications

Immunogen

Immunized with recombinant Human DNASE1 (Uniprot#: P24855; Gly19-Ala259 (Uniprot#: P24855)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for DNASE1 Antibody (2-1#)

DNASE1 Antibody (2-1#)

Immunohistochemistry-Paraffin: DNASE1 Antibody (2-1#) [NBP3-41461] -

Immunohistochemistry-Paraffin: DNASE1 Antibody (2-1#) [NBP3-41461] - Vector Red staining on IHC-P; Samples: Human Spleen Tissue; Primary Ab: 20ug/ml NBP3-41461; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Monoclonal Antibody
DNASE1 Antibody (2-1#)

Western Blot: DNASE1 Antibody (2-1#) [NBP3-41461] -

Western Blot: DNASE1 Antibody (2-1#) [NBP3-41461] - Sample: Recombinant DNASE1, Human.

Applications for DNASE1 Antibody (2-1#)

Application
Recommended Usage

Immunohistochemistry

5-20ug/mL

Western Blot

0.5-2ug/mL

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

0.01M PBS, pH7.4, 50% glycerol

Preservative

0.05% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DNASE1

DNASE1, also known as Deoxyribonuclease 1, is an endonuclease found in the zymogen granules of the nuclear envelope. Responsible for DNA fragmentation and cell death during apoptosis, DNASE1 binds to G-actin and blocks actin polymerization. Mutations in DNASE1 cause systemic lupus erythematosus (SLE), an autoimmune disease causing inflammation and tissue damage. DNASE1 is also known to treat symptoms of cystic fibrosis.

Alternate Names

deoxyribonuclease IFLJ38093, deoxyribonuclease-1, DKFZp686H0155, DNase I, DNase I, lysosomal, DNL1FLJ44902, Dornase alfa, DRNI, EC 3.1.21.1, human urine deoxyribonuclease I

Gene Symbol

DNASE1

Additional DNASE1 Products

Product Documents for DNASE1 Antibody (2-1#)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for DNASE1 Antibody (2-1#)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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