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DNMT3B Antibody (SR2574)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27699

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
Availability
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NBP3-27699-100ul
NBP3-27699-50ul

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2574

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for DNMT3B Antibody (SR2574)

Immunogen

A synthesized peptide derived from human DNMT3B (Uniprot #: Q9UBC3)

Specificity

Detects endogenous levels of total DNMT3B

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

96 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for DNMT3B Antibody (SR2574)

Western Blot: DNMT3B Antibody (SR2574) [NBP3-27699] -

Western Blot: DNMT3B Antibody (SR2574) [NBP3-27699] - Western blot analysis of (1) A549 cell lysate; (2) A431 cell lysate.

Applications for DNMT3B Antibody (SR2574)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 150mM NaCl, 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DNMT3B

DNA (cytosine-5)-methyltransferase 3B (DNAMT3b) is a C5-methyltransferase family member that is required for genome wide de novo methylation and is essential for the establishment of DNA methylation patterns during development.

Improper methylation patterns have been linked to certain human tumors and developmental abnormalities. DNMT3b antibodies are useful tools for DNA methlyation research and studies on certian cancer.

Long Name

DNA [Cytosine-5-]-Methyltransferase 3B

Alternate Names

ICF1, M.HsaIIIB

Gene Symbol

DNMT3B

Additional DNMT3B Products

Product Documents for DNMT3B Antibody (SR2574)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for DNMT3B Antibody (SR2574)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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