DOCK1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-828

Novus Biologicals, part of Bio-Techne
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NB100-828
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Canine (100%), Mouse (100%), Porcine (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all DOCK1 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-TTRKQTSVDSGIVQ corresponding to C-Terminus according to NP_001371.1.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for DOCK1 Antibody

Western Blot: DOCK1 Antibody [NB100-828]

Western Blot: DOCK1 Antibody [NB100-828]

Western Blot: DOCK1 Antibody [NB100-828] - Analysis of DOCK1 in A431 lysate using this antibody at 4 ug/ ml. Primary incubated for 12 hour. Detected by western blot using chemiluminescence.
Western Blot: DOCK1 Antibody [NB100-828]

Western Blot: DOCK1 Antibody [NB100-828]

Western Blot: DOCK1 Antibody [NB100-828] - (4ug/ml) of A431 lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 12 hour. Detected by western blot using chemiluminescence.

Applications for DOCK1 Antibody

Application
Recommended Usage

Western Blot

3 - 4 ug/ml
Application Notes
WB: Approx. 150-200 kDa band observed in A431 lysate.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: DOCK1

The DOCK1 protein is involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. It also functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. The GEF activity of the DOCK1 protein may be enhanced by ELMO1.

Long Name

Dedicator of Cytokinesis Protein 1

Alternate Names

ced5, DOCK180

Entrez Gene IDs

1793 (Human); 330662 (Mouse)

Gene Symbol

DOCK1

UniProt

NP_001371. (Human)

Additional DOCK1 Products

Product Documents for DOCK1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for DOCK1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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