DPM1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-13935

Novus Biologicals, part of Bio-Techne
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NBP2-13935
NBP2-13935-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all DPM1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the amino acids: SLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSD

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (81%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DPM1 Antibody

Immunohistochemistry-Paraffin: DPM1 Antibody [NBP2-13935]

Immunohistochemistry-Paraffin: DPM1 Antibody [NBP2-13935]

Immunohistochemistry-Paraffin: DPM1 Antibody [NBP2-13935] - Staining of human stomach, lower shows strong cytoplasmic positivity in glandular cells.

Applications for DPM1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DPM1

Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. (provided by RefSeq)

Alternate Names

CDGIEEC 2.4.1.83, dolichol monophosphate mannose synthase, dolichol-phosphate mannosyltransferase, Dolichyl-phosphate beta-D-mannosyltransferase, dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit, DPM synthase, Mannose-P-dolichol synthase, MPD synthase, MPDSDolichol-phosphate mannose synthase

Gene Symbol

DPM1

Additional DPM1 Products

Product Documents for DPM1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for DPM1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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