DPPIV/CD26 Antibody (202.36) [Janelia Fluor® 549]
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-47256JF549
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Human, Rat, Porcine (Negative), Sheep (Negative)
Applications
CyTOF-ready, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen
Label
Janelia Fluor 549
Antibody Source
Monoclonal Mouse IgG2b Kappa Clone # 202.36
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Human T cell clone
Reactivity Notes
Does not react with Porcine or Sheep.
Localization
Cell Surface
Specificity
Recognizes a glycoprotein of 110kDa, identified as CD26 (Workshop VI; Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this monoclonal antibody reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2b Kappa
Applications for DPPIV/CD26 Antibody (202.36) [Janelia Fluor® 549]
Application
Recommended Usage
CyTOF-ready
Optimal dilutions of this antibody should be experimentally determined.
Flow Cytometry
Optimal dilutions of this antibody should be experimentally determined.
Immunocytochemistry/ Immunofluorescence
Optimal dilutions of this antibody should be experimentally determined.
Immunofluorescence
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry-Frozen
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: DPPIV/CD26
Long Name
Dipeptidyl-peptidase IV
Alternate Names
CD26, DPP4
Gene Symbol
DPP4
Additional DPPIV/CD26 Products
Product Documents for DPPIV/CD26 Antibody (202.36) [Janelia Fluor® 549]
Product Specific Notices for DPPIV/CD26 Antibody (202.36) [Janelia Fluor® 549]
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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