DPS Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-54646

Novus Biologicals, part of Bio-Techne
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NBP1-54646
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all DPS Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to PDSS1(prenyl (decaprenyl) diphosphate synthase, subunit 1) The peptide sequence was selected from the middle region of PDSS1. Peptide sequence VIDDASSRRGKHTVNKIWGEKKAVLAGDLILSAASIALARIGNTTVISIL. The peptide sequence for this immunogen was taken from within the described region.

Specificity

This product is specific to Subunit or Isoform: 1.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

46 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for DPS Antibody

Western Blot: DPS Antibody [NBP1-54646]

Western Blot: DPS Antibody [NBP1-54646]

Western Blot: DPS Antibody [NBP1-54646] - Human Heart lysate, concentration 0.2-1 ug/ml.

Applications for DPS Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DPS

PDSS1 is an enzyme that elongates the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. PDSS1 catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in PDSS1 gene are a cause of coenzyme Q10 deficiency.The protein encoded by this gene is an enzyme that elongates the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in this gene are a cause of coenzyme Q10 deficiency.

Alternate Names

All-trans-decaprenyl-diphosphate synthase subunit 1, COQ1SPS, Decaprenyl pyrophosphate synthase subunit 1, decaprenyl-diphosphate synthase subunit 1, DPS, DPS1, EC 2.5.1.91, hDPS1, MGC70953, polyprenyl pyrophosphate synthetase, prenyl (decaprenyl) diphosphate synthase, subunit 1, RP13-16H11.3, subunit 1 of decaprenyl diphosphate synthase, TPRT, TPT 1, TPTcoenzyme Q1 homolog, trans-prenyltransferase, trans-prenyltransferase (TPT), Trans-prenyltransferase 1

Gene Symbol

PDSS1

UniProt

Q5T2R2 (Human)

Additional DPS Products

Product Documents for DPS Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for DPS Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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