DR3/TNFRSF25 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56380

Novus Biologicals, part of Bio-Techne
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NB100-56380
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all DR3/TNFRSF25 Antibodies »

Product Specifications

Immunogen

The antibody was developed by immunizing rabbits with a synthetic peptide corresponding to amino acids 398-417 of human DR3 protein.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DR3/TNFRSF25 Antibody

Western Blot: DR3/TNFRSF25 Antibody [NB100-56380]

Western Blot: DR3/TNFRSF25 Antibody [NB100-56380]

Western Blot: DR3/TNFRSF25 Antibody [NB100-56380] - Analysis of DR3/TNFRSF25 in HeLa cell lysate probed using DR3 antibody 0.5 ug/ml.

Applications for DR3/TNFRSF25 Antibody

Application
Recommended Usage

Western Blot

0.5-2 ug/ml
Application Notes
In HeLa, a 50 kDa band should be observed.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS containing 0.2% gelatin

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DR3/TNFRSF25

Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel cell death receptor was recently identified by several groups independently and designated DR3, Wsl-1, Apo-3, TRAMP and LARD1-5. The ligand for this novel cell death receptor has not yet been defined. DR3 is highly expressed in the tissues enriched in lymphocytes including PBL, thymus and spleen. Like TNFR1, DR3 induces apoptosis and NF-kB activation.

Long Name

Death Receptor 3

Alternate Names

Apo-3, LARD, TNFRSF25, TRAMP, WSL-1

Entrez Gene IDs

8718 (Human)

Gene Symbol

TNFRSF25

UniProt

NP_042997 (Human)

Additional DR3/TNFRSF25 Products

Product Documents for DR3/TNFRSF25 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for DR3/TNFRSF25 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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