DR3/TNFRSF25 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76474

Novus Biologicals, part of Bio-Techne
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NBP1-76474
NBP1-76474-0.025mg
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Key Product Details

Species Reactivity

Human, Mouse

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all DR3/TNFRSF25 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 16 amino acid peptide near the amino terminus of human DR3. The immunogen is located within the first 50 amino acids of DR3. Amino Acid Squence: QGGTRSPRCDCAAGDFH

Specificity

DR3 has no cross reaction to other death receptors.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

59 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for DR3/TNFRSF25 Antibody - BSA Free

Western Blot: DR3/TNFRSF25 AntibodyBSA Free [NBP1-76474]

Western Blot: DR3/TNFRSF25 AntibodyBSA Free [NBP1-76474]

Western Blot: DR3/TNFRSF25 Antibody [NBP1-76474] - Jurkat total cell lysate with DR3 antibody at 1:1000 dilution.

Immunocytochemistry/Immunofluorescence: DR3/TNFRSF25 Antibody [NBP1-76474] -

Immunocytochemistry/Immunofluorescence: DR3/TNFRSF25 Antibody [NBP1-76474] - Staining of DR3 in Jurkat cells with DR3 antibody at 5 ug/ml.

Applications for DR3/TNFRSF25 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1 ug/ml
Application Notes
A 59 kDa band can be detected in Western Blot.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Ion exchange chromatography

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DR3/TNFRSF25

Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel cell death receptor was recently identified by several groups independently and designated DR3, Wsl-1, Apo-3, TRAMP and LARD1-5. The ligand for this novel death receptor has been defined as TWEAK, also termed Apo3L. DR3 is highly expressed in the tissues enriched in lymphocytes including PBL, thymus and spleen. Like TNFR1, DR3 induces apoptosis and NF-kappaB activation.

Long Name

Death Receptor 3

Alternate Names

Apo-3, LARD, TNFRSF25, TRAMP, WSL-1

Gene Symbol

TNFRSF25

UniProt

AAQ88676 (Human)

Additional DR3/TNFRSF25 Products

Product Documents for DR3/TNFRSF25 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for DR3/TNFRSF25 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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